Clarity Bioactive Clearing Serum


A one-of-a-kind, blemish-fighting serum powered by high-linoleic acid oils and our antioxidant Cellular Bioregenerate™ Elixir to reset your natural dermal healing potential.

A serum for acne-prone skin that goes beyond bacteria and exfoliation — our one-of-a-kind Clarity serum targets blemishes at the root. Powered by high-linoleic acid oil extracts, anti-inflammatory botanicals, and our antioxidant Cellular Bioregenerate™ Elixir, this bioactive serum works deep within the skin to reset your natural dermal healing potential. Long term use of our antioxidant-packed formula fortifies against the signs of aging caused by free radicals.

For acne-prone skin and inflammatory skin concerns. More than non-comedogenic — Triple Comedogen Screened™.

  • Powerfully quenches free radicals and lowers inflammation for clearer, calmer, more rejuvenated skin.
  • Fortifies and repairs the skin barrier by increasing your skin’s natural ceramide synthesis.
  • Cultivates a healthier microbiome with selective bioactive lipids.
  • Fights blemishes + the signs of aging simultaneously.
  • Replenishes your skin’s nutrient stores to power your skin’s natural healing process.

Every Sana product is Triple Comedogen Screened™ for non-comedogenicity. Learn more about our proprietary ingredient screening process here.

30 mL 30 mL

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Glowing Results


Since using Clarity I’ve never had such clear skin. I would typically breakout on my chin and cheeks with my cycle, now I rarely ever have a breakout. I’ve never felt so confident in my own skin.


I’ve been using this for 4 days and already see a difference which was insane to me. Nothing has ever worked this fast for me. Absolutely amazing product.


Experiencing amazing results with almost 2 weeks of constant use. My skin already feels and looks radiant and most importantly I am recovering my skin’s natural moisture.

Key Ingredients


Cellular Bioregenerate™ Elixir

A meticulously crafted elixir of lipid-soluble antioxidants, including full-spectrum vitamin E, designed to mimic the cell’s innate antioxidant network, balance bioelectric systems, and restore the skin’s natural healing potential.


Restorative oil blend

A blend of 8 biocompatible, healing oils hand-selected and screened for their non-comedogenic, barrier-repairing, anti-inflammatory fatty acid content. Rich in acne-fighting linoleic acid, our hand-tailored oil blend corrects imbalances in sebum to fight blemishes before they begin.


Black cumin CO₂ extract

A vibrant, virtually-raw extract of black cumin seeds — a renowned superfood with a long history of use in traditional medicine. This powerful extract is rich in healing phytonutrients, including thymoquinone, a multifunctional antioxidant with powerful anti-inflammatory and blemish-fighting properties.

Apply 8-10 drops after toning and water-based serums and follow with the rest of The Sana Method™. Use after Flora and Eden, before SPF in the AM and retinoids in the PM.
Salvia hispanica (Chia) Seed Oil*, Borago officinalis (Borago) Seed Oil*, Echium plantagineum (Viper’s Bugloss) Seed Oil, Ribes nigrum (Blackcurrant) Seed Oil*, Citrullus lanatus (Watermelon) Seed Oil*, Squalane, Nigella sativa (Black Cumin) CO₂ Extract*, Oryza sativa (Rice) Bran CO₂ Extract*, Rubus idaeus L. (Raspberry) CO₂ Extract*, Opuntia ficus-indica L. (Prickly Pear) Seed Oil, Ubiquinone (Coenzyme Q10), Ethyl Linoleate, Ethyl Caprylate, Dimethylmethoxy Chromanol (biomimetic antioxidant), Bixa orellana (Annatto) Seed Extract, Rosmarinus officinalis (Rosemary) CO₂ Extract*, Matricaria recutita L. (German Chamomile) Oil*, Matricaria chamomilla L. (Chamomile) CO₂ Extract*, Tetrahexyldecyl Ascorbate, Tanacetum annuum (Blue Tansy) Oil*, Calendula officinalis (Calendula) CO₂ Extract, Magnolia officinalis (Magnolia Bark) Extract, Cedrus atlantica (Cedarwood) Oil*, Tocopherol, Capric/Caprylic Triglycerides, Limonene**. | *Organic. **Found in our blue tansy.

30mL / 1 fl oz | 30-60 day supply | Less than 0.75% EO content.

Phthalate-free. Paraben-free. Artificial fragrance-free. Non-photosensitizing. Non-irritating. Skin barrier safe. Ultra-clean formulations. Learn more about our ingredient philosophy here.

Streamline your skincare routine and results with an optimized regimen — The Sana Method™.
This 6-step regimen covers all the bases, ensuring that your skin is optimally, but gently cleansed, pH-balanced, and has the right balance of nutrients for optimal skin health.
To download The Sana Method™ for blemish-prone skin, click here.
To download The Sana Method™ for dry / mature / normal skin, click here.


For years, our understanding was that hyperkeratosis (overproduction) and bacterial overgrowth caused acne. So, for years, treatments for acne pretty much exclusively centered around exfoliating excess skin cells (i.e. salicylic acid) and killing bacteria (i.e. benzoyl peroxide).

While it is true that hyperkeratosis and bacterial overgrowth do contribute to breakouts (and their treatments are effective), now we know that they aren’t actually the root cause of acne. The true root cause of acne begins with two important steps: inflammation and free radical damage.

Our Clarity serum is designed to target this true root cause of acne by quenching free radicals with a synergistic antioxidant network, extinguishing inflammation with potent botanical anti-inflammatories, and protecting against future sources of inflammation like skin barrier disruption, addressing hyperkeratosis and bacterial overgrowth before they can begin.

Oils are a broader term for lipid extracts from plants, but oils are really just a combination of fatty acids, hydrocarbons, and other lipid compounds.

The different lipids in oils have different effects on the skin. For example, oleic acid, a type of fatty acid found in high levels in many plant oils, is highly comedogenic and disruptive to the skin barrier.

On the other hand, linoleic acid, another fatty acid in plant oils, fights acne, repairs the skin barrier, and balances the skin microbiome.

Different oils have different lipid compositions, some with high levels of oleic acid and other comedogenic / disruptive lipids, and some with high levels of linoleic acid and other acne-fighting lipids.

In other words, you have some oils that can be categorized as disruptive / acne-causing and others that can be categorized as acne-fighting, all based on what lipids the oils is made up of.

To make matters more complicated, many oleic acid-rich oils are often labelled as non-comedogenic (i.e. argan oil, marula oil), when they actually contain high levels of comedogenic lipids. So, you may have used oils that were labelled “non-comedogenic” when they actually had high levels of oleic acid, which may have lead to breakouts.

Our Clarity serum is mindfully formulated for acne-prone skin, with oils hand-selected for a non-comedogenic, blemish-fighting lipid profile, making it an exceptionally compatible oil for acne-prone skin.

To read more of the in-depth science behind oils for acne-prone skin, visit our blog post here.

You can absolutely use a moisturizer with Clarity! However, you may find that you don’t need to.

Moisturizers are traditionally emulsions, a blend of oil and water together. These moisturizing emulsions moisturize the skin in three ways: increasing hydration using humectants, acting as an occlusive barrier, and enhancing skin barrier repair with lipids.

Facial oils made with barrier-repairing, linoleic acid-rich oils actually have all of these same properties. In fact, they achieve these effects even more effectively than moisturizers due to the higher lipid content.

And while facial oils don’t contain humectants, the exceptionally high antioxidant content of our Clarity serum encourages the production of our skin’s natural humectants like hyaluronic acid, proteoglycans, and glycosaminoglycans, all while creating a lipid barrier to seal in moisture.

The benefit of using a facial oil as a moisturizer is that many emulsifiers used in moisturizers can be comedogenic for very sensitive acne-prone skin types, making non-comedogenic oils a better-tolerated option.

Oils shouldn’t sit on the skin. If you have had difficult getting a facial oil to absorb, there are three main reasons why. To unlock the incredible healing power of oils, we have to address all three!

Firstly (and most commonly), you may not be using a linoleic acid-rich oil. Our skin drinks up linoleic acid, utilizing it to create barrier-repairing ceramides, while other fatty acids aren’t used as readily. So, if you’re using an oil higher in other fatty acids, the oil may sit on the skin because it’s not being properly broken down.

Since Clarity is an exceptionally high linoleic acid serum, the fatty acids are easily absorbed and utilized!

Secondly, your skin may not be properly pH-balanced. To utilize linoleic acid and create ceramides, the skin must be in an acidic pH (between 4.5 and 5.5), otherwise linoleic acid won’t be absorbed. This can happen if you’re using alkaline cleansers or not using a pH-balancing toner.

Thirdly, your skin may be dehydrated. Hydrated skin absorbs all topicals better. You may be dealing with dehydration because of a disrupted skin barrier, sun damage, or nutrient deficiency in the skin (depleting your natural hydrating extracellular matrix).

To address these issues properly and experience the benefits facial oils have to offer, we recommend a comprehensive regimen that includes a gentle, hydrating cleanser, a hydrating, pH-balancing toner, and (if not pregnant or breast-feeding) a retinoid, alongside your high linoleic acid facial oil (like Clarity).

A note from Sophia

When I really think about it, Clarity was ten years in the making.

My whole skin journey - the failed supplements, the failed diets, the failed skincare products, even the timing of when my health insurance expired (impeding my last-ditch access to drug-based treatments), and, as a result, the desperation to solve the puzzle through research - was the catalyst for the creation of the Clarity formula. If the "holy grail" that worked for everyone had really truly worked for me, Clarity may not have made it to the skincare market.
Even though my cystic acne journey felt grueling and never-ending, I am thankful today knowing that my experience has culminated in a product (and, now, regimen) that brings healing to many others who were in the same exact position as me.